After thrombolytics, which blood pressure target should be maintained?

After thrombolytics, which blood pressure target should be maintained?

• A. less than 180/105
• B. less than 170/90
• C. less than 190/110
• D. less than 160/90

Answer: (A)

After giving thrombolytics for acute ischemic stroke, the goal is to prevent bleeding without compromising perfusion to the brain. The recommended target is to keep blood pressure below 180 systolic and below 105 diastolic (180/105) during thrombolysis and for about the first 24 hours afterward. This balance reduces the risk of hemorrhagic transformation associated with thrombolytics, while still maintaining enough cerebral blood flow to the penumbra. If BP rises above this threshold, it should be lowered gradually with IV antihypertensives like labetalol, nicardipine, or clevidipine.

After giving thrombolytics for acute ischemic stroke, the goal is to prevent bleeding without compromising perfusion to the brain. The recommended target is to keep blood pressure below 180 systolic and below 105 diastolic (180/105) during thrombolysis and for about the first 24 hours afterward. This balance reduces the risk of hemorrhagic transformation associated with thrombolytics, while still maintaining enough cerebral blood flow to the penumbra. If BP rises above this threshold, it should be lowered gradually with IV antihypertensives like labetalol, nicardipine, or clevidipine.